Read the following passage carefully and then choose the best option to fit each space.

Despite the wealth of information campaigns telling people about global warming and its causes, most people have yet to realize how severe the problem is. Coming climate changes could alter as much as one third of plant and animal habitats ___(1)___ the end of the 22nd century. These changes could in turn cause widespread extinctions among plant and animal ___(2)___ around the globe.
Coastal and island habitats are perhaps in the greatest danger ___(3)___ they face the combined threats of warming oceans and rising sea ___(4)___. As habitats change, many animals will come under intense pressure to find more suitable homes for themselves. Mass ___(5)___ of at least some animals are certainly to be expected, but the fact remains that many animals will simply not be able to move fast enough.